MEST-C histological score on the kidney biopsy

MEST-C scoring system

tests per year, international, once, per biopsy

“The prognostic MEST-C scoring system for kidney biopsies in IgAN consists of three proliferative and inflammatory parameters (mesangial proliferation, endocapillary hypercellularity and crescents) and two fibrotic parameters (segmental glomerulosclerosis and tubulointerstitial atrophy and fibrosis)”

Clin Kidney J 2025, The 2025 KDIGO IgA nephropathy guideline update: an ERA Immunonephrology Working Group perspective, 2025-11

Kind of source

Clinical guideline

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2026-11-06

Daily check

Quote found at the source on 2026-11-06

What to know

Part of the pathology report; the International IgAN Prediction Tool combines it with clinical factors.

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IgA nephropathyPathology reports