Review of second-line tricyclic antidepressant
review regularly
tests per year, UK, review regularly
“Consider tricyclic antidepressants (TCAs) as second‑line treatment for people with IBS if laxatives, loperamide or antispasmodics have not helped. Start treatment at a low dose (5 mg to 10 mg equivalent of amitriptyline), taken once at night, and review regularly.”
NICE CG61 Irritable bowel syndrome in adults, recommendations, 2026-11-06
- Kind of source
- Clinical guideline
- Read on
- 2026-11-06
- Daily check
- Quote found at the source on 2026-11-06
- What to know
- Prescribed only after first-line medicines have not helped; the guideline gives no interval.
Used in
Kept as evidence; no figure on the platform is computed from it yet.