New (incident) cases of GERD worldwide, 2021

324.1 million

people per year (incident cases), worldwide

“From 1990 to 2021, incident cases increased from 180.0 million to 324.1 million (+80.1%), and prevalent cases increased from 450.8 million to 825.6 million (+83.2%).”

Dong et al., Global burden of gastroesophageal reflux disease, 1990-2021, with projections to 2040 (GBD 2021), Dis Esophagus 2025, 2025-11-01

Kind of source

Peer-reviewed study

Read on

2026-11-06

Daily check

Quote found at the source on 2026-11-06

What to know

GBD models GERD as episodic, so incident cases count new symptomatic episodes in the year, which is why they are large relative to prevalence.

About

Acid reflux (GERD)