New cases of depressive disorders worldwide, 2021

357.44 million

new cases per year, worldwide

“In 2021, there were 357.44 million incident cases, 332.41 million prevalent cases and 56.33 million DALYs.”

British Journal of Psychiatry 2025, Global, regional and national burden of depressive disorders and attributable risk factors, from 1990 to 2021 (GBD 2021), 2025-10

Kind of source

Peer-reviewed study

Read on

2026-11-06

Daily check

Quote found at the source on 2026-11-06

What to know

GBD 2021 modelled estimate. Counts depressive episodes that began in the year (major depressive and dysthymia), so a person can be counted more than once across years.

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Depression